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I / Homeostasis · Cellular maintenance · 03
Membrane turnover & maturation
How does a cell remove membranes without destroying its own compartments?

01 / The Central Question
Building membranes is only one part of keeping a cell healthy. Old or damaged material must also be enclosed, delivered to the right compartment and broken down safely.
If cells cannot break down unwanted membranes and damaged components, these materials may accumulate. This is relevant to understanding cellular changes associated with ageing and diseases involving impaired cellular recycling.
02 / Mechanisms & Discoveries
How these processes work
Choose a question below to read how the process works, what research has shown and which questions remain open. Each explanation also links to the original papers and press releases.
01 / 03Recognizing and breaking down the right membranesHow can a cell digest unwanted membranes while protecting others?Read the explanation02 / 03Recognizing when membranes are ready to fuseHow does a cell decide when a membrane compartment should fuse?Read the explanation03 / 03Reshaping and removing damaged mitochondriaHow are damaged mitochondria prepared for recycling?Read the explanation